Abstract
Introduction. Accuracy and consistency in emergency department (ED) triage are essential for patient safety, yet variability in nurse-assigned triage levels persists despite standardized protocols. This study explored the potential of ChatGPT as a retrospective evaluator of triage appropriateness according to the Tuscan Triage System.
Methods. Fifty real-world clinical scenarios were randomly extracted from an urban ED in Tuscany, Italy. Two certified triage experts independently reviewed each case, with a third resolving disagreements. ChatGPT (GPT-4o, OpenAI) was then asked to assess whether the original triage level was appropriate. Model outputs were compared with the expert-defined reference standard. Agreement, Cohen’s kappa, macro-averaged precision, recall, F1-score, and class-specific sensitivity and specificity were calculated.
Results. Exact agreement between ChatGPT and experts was observed in 46% of cases. Under-triage discrepancies were more frequent than over-triage (38% vs 16%). Cohen’s kappa was 0.243. Performance was better in high-complexity cases (κ=0.313; F1=0.704) and lower in moderate- and low-complexity categories. Most errors involved adjacent triage levels.
Discussion. ChatGPT showed limited-to-moderate agreement with expert triage assessment, with better performance in more critical scenarios. Although unsuitable for autonomous triage, it may have potential as a retrospective quality assurance tool. Further refinement and clinical validation are needed before use in audit or decision-support processes.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2026 Christian Ramacciani Isemann, Simona Burresi, Sabina Innocenti, Lorenzo Righi

