Abstract
Introduction. Chronic Limb-Threatening Ischemia (CLTI) represents the advanced stage of Peripheral Artery Disease (PAD), a condition with increasing prevalence worldwide due to the rising burden of risk factors and comorbidities, and consequently, escalating healthcare costs. CLTI is a highly morbid condition, often leading to limb loss, chronic pain, and significantly impaired health-related quality of life. Despite its severe consequences, CLTI remains underrecognized. Patients often realise the severity of the disease at a late stage, when revascularisation attempts may no longer be useful. Primary prevention interventions are essential for early diagnosis and correct patient pathway. The trained nurse could have an important role in the community in identifying and managing this disease. This scoping review aims to evaluate the literature on knowledge of nurses about preventive interventions and therapeutic education, and how, and raising awareness of this disease among professionals and individuals from a community medicine perspective, this topic can be developed using the potential of nurses in the team.
Methods. The Joanna Briggs Institute Reviewers’ Manual and the framework developed by Arksey and O’Malley were used as the guidelines for the scoping review that is suggested in this protocol. Accordingly, the PCC (Population, Concept, Context) model was adopted. The Preferred Reporting Items for Systematic and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) will be followed for reporting the research and the results. The databases will include MEDLINE/ PubMed, Cochrane, CINAHL and grey literature sources.
Expected results. The main expected results will be the mapping of available evidence and the implementation of knowledge regarding available nursing interventions as well as improved adherence to educational interventions.
References
1. Conte MS, Bradbury AW, Kolh P, et al. Global vascular guidelines on the management of chronic limb-threatening ischemia. J Vasc Surg. 2019;69(6 Suppl):3S–125S.e40. https://doi.org/10.1016/j.jvs.2019.02.016
2. Mazzolai L, Teixido-Tura G, Lanzi S, et al. 2024 ESC guidelines for the management of peripheral arterial and aortic diseases. Eur Heart J. 2024;45(36):3538–3700. https://doi.org/10.1093/eurheartj/ehae179
3. Secemsky EA, Kirksey L, Quiroga L, et al. Impact of intensity of vascular care preceding major amputation among patients with chronic limb-threatening ischemia. Circ Cardiovasc Interv. 2024;17(1):e012798. https://doi.org/10.1161/CIRCINTERVENTIONS.122.012798
4. Catalano M. Ischemic limb disease: epidemiology and clinical burden in Italy. Technol Innov Med. 2021;6:265–273.
5. Horváth L, Németh N, Fehér G, Kívés Z, Endrei D, Boncz I. Epidemiology of peripheral artery disease: narrative review. Life (Basel). 2022;12(7):1041. https://doi.org/10.3390/life12071041
6. Castro-Dominguez Y, Shishehbor MH. Team-based care in patients with chronic limb-threatening ischemia. Curr Cardiol Rep. 2022;24(3):217–223. https://doi.org/10.1007/s11886-022-01643-2
7. Neville RF. Management of peripheral arterial disease in the context of a multidisciplinary limb program. Front Cardiovasc Med. 2024;11:1368655. https://doi.org/10.3389/fcvm.2024.1368655
8. Soendergaard SF, Simony A, Christiansen JL, Laursen HS, Dahl M. Patients with chronic limb-threatening ischemia: experiences of their disease, treatment, and care in a cross-sectoral setting. A scoping review. J Vasc Nurs. 2024;42(4):240–250. https://doi.org/10.1016/j.jvn.2024.08.002
9. Monaro S, West S, Gullick J. Chronic limb-threatening ischaemia and reframing the meaning of 'end'. J Clin Nurs. 2021;30(5–6):687–700. https://doi.org/10.1111/jocn.15591
10. Westphaln KK, Regoeczi W, Masotya M, et al. From Arksey and O’Malley and beyond: Customizations to enhance a team-based, mixed approach to scoping review methodology. MethodsX. 2021;8:101375. https://doi.org/10.1016/j.mex.2021.101375
11. Peters MDJ, Godfrey C, McInerney P, et al. Best practice guidance and reporting items for the development of scoping review protocols. JBI Evid Synth. 2022;20(4):953–968. https://doi.org/10.11124/JBIES-21-00242
12. Tricco AC, Lillie E, Zarin W, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467–473. https://doi.org/10.7326/M18-0850
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